A MARINE ANTHRAQUINONE SZ-685C OVERRIDES ADRIAMYCIN-RESISTANCE IN BREAST CANCER CELLS THROUGH SUPPRESSING AKT SIGNALING

A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling

Breast cancer remains a major health problem worldwide.While chemotherapy represents an important therapeutic modality against breast cancer, limitations in the clinical use of chemotherapy remain formidable because of chemoresistance.The HER2/PI-3K/Akt pathway has been demonstrated to play a causal role in conferring a broad chemoresistance in bre

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Effect of sonotherapy on symptoms of carpal tunnel syndrome

Admission.Carpal tunnel syndrome (CTS) is one of the most common peripheral neuropathies of the upper limb, which is caused by an increase in pressure in the wrist canal or a decrease in its volume leading to compression and mediated nerve endothelial dysfunction.This disease significantly affects the quality of life of patients, limiting its manua

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Fortified-Grid: Fortifying Smart Grids through the Integration of the Trusted Platform Module in Internet of Things Devices

This paper presents a hardware-assisted security primitive that integrates the Trusted Platform Module (TPM) into IoT devices for authentication in smart Ice Scoop/Holder Combos grids.Data and device security plays a pivotal role in smart grids since they are vulnerable to various attacks that could risk grid failure.The proposed Fortified-Grid sec

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Combining Rigorous Requirements Specifications with Low-Code Platforms to Rapid Development Software Business Applications

Low-code development platforms have gained popularity Baseball as an effective solution to address urgent market demands for software applications.These platforms have often overcome challenges faced by traditional software development processes, including requirements engineering processes, as they tend to incorporate the requirements in their pro

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